A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.
In recent months I’ve highlighted two excellent iPad apps by OnScreen Science that center around a 3D model of DNA. For the sake of completeness, let me now mention the third and final member of the ...
One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...
MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...
To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...
With GROVER, a new large language model trained on human DNA, researchers could now attempt to decode the complex information hidden in our genome. GROVER treats human DNA as a text, learning its ...
In a recent study published in PNAS, researchers introduced the Genomic Pre-trained Network (GPN), a multispecies model developed to learn genome-wide variant effects by self-supervised pretraining on ...
Single-cell analysis helps uncover how the BK virus replicates, opening the door to new drug targets. BK polyomavirus (BKPyV) is a major cause of kidney transplant failure. Without a complete ...
BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research reveals new aspects of BKPyV replication, offering possible drug targets ...