DNA, often called the blueprint of life, is built from four chemical building blocks known as deoxy-nucleoside triphosphates ...

New research from the University of Wisconsin–Madison reveals that dysfunction in a protein essential to maintaining ...

A study reveals that a protein called RPA is essential for maintaining chromosome stability by stimulating telomerase. New findings from the-Madison suggest that problems with a key protein that helps ...

They observe how the mobile DNA LINE-1 copies its sequence in human cells, revealing the precise mechanism of the ORF2p gene.

Sometimes the unintended consequences of a treatment can seem worse than the disease. That's certainly the case for patients ...

Scientists have discovered how LINE-1, a “jumping gene” that makes up 17% of the human genome, inserts itself into DNA. Using ...

DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...

Long Interspersed Nuclear Element-1 (LINE-1 or L1) is the only active, self-copying genetic element in the human ...

Mayo Clinic researchers have identified a protein that acts like a traffic controller for DNA, preventing damage during cell division—a discovery that could lead to new cancer therapies, according to ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...