While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...
In melanoma, we've now shown that damage from sunlight primes the DNA by creating 'premutations' that then give way to full mutations during DNA replication." Gerd Pfeifer, Ph.D., VAI professor and ...
A phase 1 trial of JS001, a monoclonal antibody targeting programmed death-1 (PD-1) in patients with advanced or recurrent malignancies. This is an ASCO Meeting Abstract from the 2017 ASCO Annual ...
Johannes holds an MSci in Neuroscience from King’s College London, where he worked on projects involving Alzheimer’s disease and Fragile X syndrome. Johannes holds an MSci in Neuroscience from King’s ...
If they happen to do this just before the two DNA strands are cleaved as part of the cell replication process, the protons can become trapped on the wrong side, leading to a DNA mismatch and a ...
DNA sequences that can fold into shapes other than the classic double helix tend to have higher mutation rates than other regions in the human genome. New research shows that the elevated mutation ...
This goes against one of the key assumptions of the theory of evolution. When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works. Genetic changes that ...
Bowel cancer cells have the ability to regulate their growth using a genetic on-off switch to maximize their chances of survival, a phenomenon that's been observed for the first time by researchers at ...
The DNA mutations that drive evolution are generally thought to be fairly random, but a new study suggests there’s some order to the chaos. Comparing the genomes of hundreds of plants grown in a lab, ...
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