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Lipid nanoparticle structure shapes cell uptake: Cubosomes fuse with membranes for efficient delivery
Scientists have discovered that the internal shape of tiny drug-delivery particles—called lipid nanoparticles—has a big impact on how well our cells absorb them, paving the way to more efficient ...
Changing just one atom in a COVID-19 vaccine lipid redirects delivery from the liver to the spleen, improving tumor ...
Schematic illustration showing the classification of lipid‐based nanocarriers (LBNCs) (including liposomes, micelles, nanoemulsions, SLNs/NLCs, LNPs, BLNs, SRLNCs) and their targeted delivery to ...
Membrane proteins and membrane lipids are essential partners in various biological processes, and elucidating their ...
Interest in lipid nanoparticles (LNPs) as delivery vehicles for precision therapies in genetic diseases and cancers remains at an all-time high. Now, scientists from the University of Pennsylvania, ...
LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...
“We’ve never had such an in-depth map of the CD1 lipidome available,” said Patricia Barral, an immunologist at King’s College London who was not involved with the work. “It will enable us to start ...
Using artificial intelligence (AI), researchers headed by a team at Massachusetts Institute of Technology (MIT) have come up with a new way to design nanoparticles that can more efficiently deliver ...
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