Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells.

Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...

In 1869, Swiss scientist Friedrich Miescher isolated a mysterious substance from cell nuclei—an overlooked finding that would ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

When cells in the body die, they release DNA. This DNA, known as cell-free DNA (cfDNA), makes its way into the bloodstream where it gets chopped up by enzymes, and in minutes to hours, the liver pulls ...

Differences in the pattern of a biochemical modification called DNA methylation in blood-generating cells and their progeny can be used to accurately track clones through differentiation. This ...