A designer version of the tau protein, developed by a team led by UT Southwestern Medical Center researchers, maintains its ...

The pathway leading to the telltale sign of ALS, protein aggregation in the cytoplasm of motor neurons, has been revealed. Researchers from the University of California – San Diego (CA, USA) have ...

Protein low-complexity domains (LCDs) stack together to form dynamic liquid droplets within the cell; alas, some pathogenic mutations in these regions encourage aggregation beyond this temporary ...

Researchers have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail.

Could measuring protein clumps in our cells be a new way to find out our risk of getting age-related diseases? Professor Dorothee Dormann and Professor Edward Lemke of Johannes Gutenberg University ...

Mutations in or mislocalization of RNA-binding proteins, such as TDP-43 and FUS, are linked to protein aggregation in frontotemporal dementia and amyotrophic lateral sclerosis. Now, researchers led by ...

Durable analytical instruments expedite the study of misfolded proteins linked to neurodegenerative diseases. To overcome these limitations, scientists developed the real-time quaking-induced ...

Researchers at the VIB-KU Leuven Center for Microbiology and the VIB-KU Leuven Center for Brain & Disease Research revealed a mechanism involving protein aggregation that allows bacteria to enter a ...

A designer version of the tau protein, developed by a team led by UT Southwestern Medical Center researchers, maintains its ...

A novel system to control protein aggregation in a model of Parkinson’s disease may answer longstanding questions about how the disease begins and spreads, according to a new study published March 9 ...