The current path to CAR-T cell therapy is, by any measure, a logistical ordeal. A patient’s immune cells must be drawn out of ...

The powerful gene-editing technique CRISPR–Cas9 might offer a way to make safer, more effective cancer-fighting immune cells ...

Endometrial cancer is the most common gynecologic cancer in the United States and is one of the few cancers in which survival ...

Immunotherapy has transformed cancer treatment by harnessing the body's own immune system to fight disease. But many ...

The researchers say that, to their knowledge, this is the first demonstration of programmable, site-specific integration of a ...

For years, one of the most powerful weapons against certain blood cancers, called CAR-T cell therapy, has required an ...

Mesothelin-targeted CAR-NKT cells leveraged three recognition mechanisms, potentially limiting antigen escape and ...

Finding an effective treatment for osteosarcoma, the most common type of bone cancer in children and young adults, has ...

Researchers at UC San Francisco have now developed a way to reprogram these cancer-fighting cells directly inside the body. This new method could remove the need for external manufacturing, ...

Developing the system required careful fine-tuning. Too much stimulation can wear out immune cells, while too little allows ...