Early-stage lung adenocarcinoma alters DNA methylation, mRNA transcription, and protein expression in adjacent tissues, exhibiting either steep changes at the tumor boundaries or shallow changes ...
Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...
A recent study led by Tiffany Schmidt, Ph.D., associate professor of Ophthalmology and of Neurobiology in the Weinberg ...
Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...
State Key Laboratory for Quality and Safety of Agro-Products, Key Laboratory of Biotechnology in Plant Protection of MARA, Zhejiang Key Laboratory of Green Plant Protection, Institute of Plant ...
This important study examines the potential role of ARHGAP36 transcriptional regulation by FOXC1 in controlling sonic hedgehog signaling in human neuroblastoma. While there are many solid findings ...
A team of Chinese scientists has uncovered a hidden 3D structure in rice DNA that allows the crop to grow more grain while ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...
A top US regulator plans to unveil a faster approach to approving custom gene-editing treatments, a move designed to unleash a wave of industry investment that will yield cures for patients with rare ...
DNA polymerases lie at the heart of diagnostic techniques like polymerase chain reaction (PCR), enabling early detection of ...
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