Adipose Triglyceride Lipase (ATGL) can undergo activation through two different pathways: transcriptionally and through post-translational modification.

Jul 26, 2025 · Adipose Triglyceride Lipase (ATGL) is an enzyme that helps manage fat in our bodies, influencing energy levels and metabolic health. It breaks down stored fats to supply …

Adipose triglyceride lipase (ATGL) is defined as a key enzyme that initiates the hydrolysis of triglycerides to release fatty acids, playing a crucial role in energy metabolism and …

Mar 21, 2024 · ATGL is a key enzyme in intracellular lipolysis and plays an important role in metabolic and cardiovascular diseases. ATGL is tightly regulated by a known set of protein …

Adipose triglyceride lipase (ATGL) is the key-enzyme for the release of fatty acids (FAs) from triacylglycerol (TG) stores during intracellular lipolysis producing FAs used for energy production.

Jun 9, 2025 · ATGL is a triglyceride lipase that catalyzes the hydrolysis of triglycerides to diacylglycerols and free fatty acids. The enzyme exhibits a high degree of substrate specificity, …

The PNPLA2 gene provides instructions for making an enzyme called adipose triglyceride lipase (ATGL). The ATGL enzyme plays a role in breaking down fats called triglycerides, which are …

Dec 31, 2021 · Adipose triglyceride lipase (ATGL) is the rate-limiting enzyme that catalyzes the first step of TG breakdown to glycerol and fatty acids.

Jul 22, 2025 · Adipose triglyceride lipase (ATGL) is the primary enzyme that initiates the breakdown of fat stored within the body’s adipose tissue (fat cells). It controls the release of …

Jun 8, 2022 · Here we identified adipose triglyceride lipase (ATGL, also known as patatin-like phospholipase domain containing 2 (PNPLA2)) as a candidate biosynthetic enzyme for …