Feb 25, 2021 · Currently, the precise mechanism of ICIs-associated pancreatic injury has not been fully explored. This paper summarizes incidence, diagnosis, clinical characteristics, potential …

Results: Among 1516 melanoma patients receiving ICI therapy, 204 patients exhibited ≥CTCAE II° lipase elevation. Of these patients, 41 (20.1%) had symptoms suggestive of pancreatitis. …

Jun 7, 2023 · With the increased use of immune checkpoint inhibitors (ICI), rare ICI-associated pancreatic adverse events are being recognized. Here, we describe the clinical characteristics and …

Mar 23, 2025 · We found that while this condition is rare, it can lead to long-term health issues like diabetes mellitus and exocrine pancreatic insufficiency, even after cancer treatment ends.

Aug 1, 2023 · ICI-induced pancreatic injury (ICI-PI) ranges from asymptomatic hyperlipasemia to symptomatic acute pancreatitis (AP), which can be fatal. 2 Hyperlipasemia or hyperamylasemia has …

Dec 2, 2025 · Explore the link between immunotherapy and pancreatitis. Learn about symptoms, risk factors, diagnosis, and management of this rare immune-related side effect.

Immunotherapy is increasingly gaining applicability for several malignancies. While the survival of several malignancies has dramatically improved, immune-related adverse events (irAEs) can occur …

Jun 10, 2025 · Background/Objectives: The increasing use of immune checkpoint inhibitors (ICIs) in cancer treatment has led to a rise in immune-related adverse events (irAEs), including pancreatic injury.

Mar 19, 2025 · By using a pharmacovigilance database, we discovered an elevated risk of pancreatitis following ICIs therapy, especially with PD-1 inhibitors. Meanwhile, risk factors for ICIs-P remain …

Currently, the precise mechanism of ICIs-associated pancreatic injury has not been fully explored. This paper summarizes incidence, diagnosis, clinical characteristics, potential mechanisms, and treatment …