
- Junk Food Binge May Alter Brain Insulin Response - Medscape- Mar 11, 2025 · Excessive consumption of ultraprocessed, calorie-rich snacks even for a short period may result in fat accumulation in the liver and a temporary impairment of insulin function in the brain. 
- Vildagliptin: A Novel Oral Therapy for Type 2 Diabetes Mellitus- Insulin resistance and ß-cell function were evaluated using homeostasis model assessments, which compare a patient's fasting glucose level and the predicted glucose level based on a computerized ... 
- Tirzepatide Tops TRT for Men With Hypogonadism and Obesity- Jul 23, 2025 · In a study of 83 men with obesity, functional hypogonadism, and insulin resistance, those treated with the dual glucose-dependent insulinotropic peptide and glucagon-like peptide 1 (GLP-1 ... 
- Metal Ions: The Next Frontier in Diabetes Management? - Medscape- May 15, 2025 · In turn, oxidative stress can result in peripheral insulin resistance and impairment of islet beta-cell function, triggering diabetes and diabetic complications. 
- Insulin Regulates Brain Function, but how Does it get There?- As insulin is not required for GLUT1- or GLUT3-mediated glucose transport, insulin is not needed for glucose transport into most brain cells. 
- Repurposed Drugs Show Promise in Preventing T1D Progression- Sep 19, 2025 · New data suggest antithymocyte globulin, verapamil, and baricitinib might help preserve beta cell function in new-onset type 1 diabetes. 
- Are Post-Meal Insulin Surges Beneficial? - Medscape- Jan 5, 2024 · Rapid surges in insulin following a meal are associated with favorable long-term cardiometabolic benefits, including improvements in beta cell function and a lower risk for the … 
- Is Intermittent Fasting Safe and Beneficial? - Medscape- Feb 10, 2025 · Both diets reduced neuronal insulin resistance and the pace of brain aging. Both improved memory and executive function, with the 5:2 dietary pattern showing superiority. 
- What Else Can GLP-1 Drugs Do for Your Patients? - Medscape- Apr 7, 2025 · Glycemic Control The GLP-1 hormone plays a vital role in the regulation of blood sugar levels. Drugs that mimic its action enhance insulin secretion in a glucose-dependent manner and … 
- The Undervalued Medical Power of Muscle - Medscape- Jun 13, 2025 · Skeletal muscle regulates more than 75% of insulin-mediated glucose disposal, helping control glucose and lipids while reducing the risk for metabolic diseases like type 2 diabetes.