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  1. Junk Food Binge May Alter Brain Insulin Response - Medscape

    Mar 11, 2025 · Excessive consumption of ultraprocessed, calorie-rich snacks even for a short period may result in fat accumulation in the liver and a temporary impairment of insulin function in the brain.

  2. Vildagliptin: A Novel Oral Therapy for Type 2 Diabetes Mellitus

    Insulin resistance and ß-cell function were evaluated using homeostasis model assessments, which compare a patient's fasting glucose level and the predicted glucose level based on a computerized ...

  3. Tirzepatide Tops TRT for Men With Hypogonadism and Obesity

    Jul 23, 2025 · In a study of 83 men with obesity, functional hypogonadism, and insulin resistance, those treated with the dual glucose-dependent insulinotropic peptide and glucagon-like peptide 1 (GLP-1 ...

  4. Metal Ions: The Next Frontier in Diabetes Management? - Medscape

    May 15, 2025 · In turn, oxidative stress can result in peripheral insulin resistance and impairment of islet beta-cell function, triggering diabetes and diabetic complications.

  5. Insulin Regulates Brain Function, but how Does it get There?

    As insulin is not required for GLUT1- or GLUT3-mediated glucose transport, insulin is not needed for glucose transport into most brain cells.

  6. Repurposed Drugs Show Promise in Preventing T1D Progression

    Sep 19, 2025 · New data suggest antithymocyte globulin, verapamil, and baricitinib might help preserve beta cell function in new-onset type 1 diabetes.

  7. Are Post-Meal Insulin Surges Beneficial? - Medscape

    Jan 5, 2024 · Rapid surges in insulin following a meal are associated with favorable long-term cardiometabolic benefits, including improvements in beta cell function and a lower risk for the …

  8. Is Intermittent Fasting Safe and Beneficial? - Medscape

    Feb 10, 2025 · Both diets reduced neuronal insulin resistance and the pace of brain aging. Both improved memory and executive function, with the 5:2 dietary pattern showing superiority.

  9. What Else Can GLP-1 Drugs Do for Your Patients? - Medscape

    Apr 7, 2025 · Glycemic Control The GLP-1 hormone plays a vital role in the regulation of blood sugar levels. Drugs that mimic its action enhance insulin secretion in a glucose-dependent manner and …

  10. The Undervalued Medical Power of Muscle - Medscape

    Jun 13, 2025 · Skeletal muscle regulates more than 75% of insulin-mediated glucose disposal, helping control glucose and lipids while reducing the risk for metabolic diseases like type 2 diabetes.